Altered Responsiveness to TGF-β and BMP and Increased CD45+ Cell Presence in Mitral Valves are Unique Features of Ischemic Mitral Regurgitation

OBJECTIVE: Ischemic mitral regurgitation (IMR) often develops after an ischemic event, which results in distortion of the valvulo-ventricular complex and incomplete mitral valve (MV) leaflet coaptation. After left ventricle (LV) ischemic events, only some patients develop IMR. The susceptibility of...

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Detaylı Bibliyografya
Yayımlandı:Arterioscler Thromb Vasc Biol
Asıl Yazarlar: Castillero, Estibaliz, Howsmon, Daniel P., Rego, Bruno V., Keeney, Samuel, Driesbaugh, Kathryn H., Kawashima, Takayuki, Xue, Yingfei, Camillo, Chiara, George, Isaac, Gorman, Robert C., Gorman, Joseph H., Sacks, Michael S., Levy, Robert J., Ferrari, Giovanni
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159877/
https://ncbi.nlm.nih.gov/pubmed/33827255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.121.316111
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