Mitral valve leaflet response to ischaemic mitral regurgitation: from gene expression to tissue remodelling

Ischaemic mitral regurgitation (IMR), a frequent complication following myocardial infarction (MI), leads to higher mortality and poor clinical prognosis if untreated. Accumulating evidence suggests that mitral valve (MV) leaflets actively remodel post MI, and this remodelling increases both the sev...

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Enregistré dans:
Détails bibliographiques
Publié dans:J R Soc Interface
Auteurs principaux: Howsmon, Daniel P., Rego, Bruno V., Castillero, Estibaliz, Ayoub, Salma, Khalighi, Amir H., Gorman, Robert C., Gorman, Joseph H., Ferrari, Giovanni, Sacks, Michael S.
Format: Artigo
Langue:Inglês
Publié: The Royal Society 2020
Sujets:
Life Sciences–Engineering interface
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276554/
https://ncbi.nlm.nih.gov/pubmed/32370692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2020.0098
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