Mitral valve leaflet response to ischaemic mitral regurgitation: from gene expression to tissue remodelling

Ischaemic mitral regurgitation (IMR), a frequent complication following myocardial infarction (MI), leads to higher mortality and poor clinical prognosis if untreated. Accumulating evidence suggests that mitral valve (MV) leaflets actively remodel post MI, and this remodelling increases both the sev...

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Bibliografiske detaljer
Udgivet i:J R Soc Interface
Main Authors: Howsmon, Daniel P., Rego, Bruno V., Castillero, Estibaliz, Ayoub, Salma, Khalighi, Amir H., Gorman, Robert C., Gorman, Joseph H., Ferrari, Giovanni, Sacks, Michael S.
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2020
Fag:
Life Sciences–Engineering interface
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276554/
https://ncbi.nlm.nih.gov/pubmed/32370692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2020.0098
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