Mitral valve leaflet response to ischaemic mitral regurgitation: from gene expression to tissue remodelling

Ischaemic mitral regurgitation (IMR), a frequent complication following myocardial infarction (MI), leads to higher mortality and poor clinical prognosis if untreated. Accumulating evidence suggests that mitral valve (MV) leaflets actively remodel post MI, and this remodelling increases both the sev...

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Detalhes bibliográficos
Publicado no:J R Soc Interface
Main Authors: Howsmon, Daniel P., Rego, Bruno V., Castillero, Estibaliz, Ayoub, Salma, Khalighi, Amir H., Gorman, Robert C., Gorman, Joseph H., Ferrari, Giovanni, Sacks, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2020
Assuntos:
Life Sciences–Engineering interface
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276554/
https://ncbi.nlm.nih.gov/pubmed/32370692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2020.0098
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