Disruption of tmc1/2a/2b Genes in Zebrafish Reveals Subunit Requirements in Subtypes of Inner Ear Hair Cells

Detection of sound and head movement requires mechanoelectrical transduction (MET) channels at tips of hair-cell stereocilia. In vertebrates, the transmembrane channel-like (TMC) proteins TMC1 and TMC2 fulfill critical roles in MET, and substantial evidence implicates these TMCs as subunits of the M...

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Vydáno v:J Neurosci
Hlavní autoři: Smith, Eliot T., Pacentine, Itallia, Shipman, Anna, Hill, Matthew, Nicolson, Teresa
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2020
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275854/
https://ncbi.nlm.nih.gov/pubmed/32371604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0163-20.2020
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