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Function and Dysfunction of TMC Channels in Inner Ear Hair Cells

The TMC1 channel was identified as a protein essential for hearing in mouse and human, and recognized as one of a family of eight such proteins in mammals. The TMC family is part of a superfamily of seven branches, which includes the TMEM16s. Vertebrate hair cells express both TMC1 and TMC2. They ar...

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Foilsithe in:Cold Spring Harb Perspect Med
Main Authors: Corey, David P., Akyuz, Nurunisa, Holt, Jeffrey R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450785/
https://ncbi.nlm.nih.gov/pubmed/30291150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a033506
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