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Marginal zone SIGN-R1(+) macrophages are essential for the maturation of germinal center B cells in the spleen
The mechanisms that regulate germinal center (GC) B cell responses in the spleen are not fully understood. Here we use a combination of pharmacologic and genetic approaches to delete SIGN-R1(+) marginal zone (MZ) macrophages and reveal their specific contribution to the regulation of humoral immunit...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7275705/ https://ncbi.nlm.nih.gov/pubmed/32424104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1921673117 |
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