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Marginal zone SIGN-R1(+) macrophages are essential for the maturation of germinal center B cells in the spleen

The mechanisms that regulate germinal center (GC) B cell responses in the spleen are not fully understood. Here we use a combination of pharmacologic and genetic approaches to delete SIGN-R1(+) marginal zone (MZ) macrophages and reveal their specific contribution to the regulation of humoral immunit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Pirgova, Gabriela, Chauveau, Anne, MacLean, Andrew J., Cyster, Jason G., Arnon, Tal I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275705/
https://ncbi.nlm.nih.gov/pubmed/32424104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1921673117
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