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Spleen deposition of Cryptococcus neoformans capsular Glucuronoxylomannan in rodents occurs in red pulp macrophages and not marginal zone macrophages expressing the C-type lectin SIGN-R1

The fate of microbial polysaccharides in host tissues is an important consideration because these compounds are often immune modulators. Splenic marginal zone macrophages that express the C-type lectin receptor SIGN-R1, take up neutral polysaccharides such as dextran and the capsular polysaccharide...

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Autors principals: De Jesus, Magdia, Park, Chae Gyu, Su, Ya, Goldman, David L., Steinman, Ralph M., Casadevall, Arturo
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828395/
https://ncbi.nlm.nih.gov/pubmed/18324494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13693780701747182
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