Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone

Specialized B cells residing in the splenic marginal zone (MZ) continuously survey the blood for antigens and are important for immunity to systemic infections. However, the cues that uniquely attract cells to the MZ have not been defined. Previous work demonstrated that mice deficient in cannabinoi...

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Autores principales: Muppidi, Jagan R., Arnon, Tal I., Bronevetsky, Yelena, Veerapen, Natacha, Tanaka, Masato, Besra, Gurdyal S., Cyster, Jason G.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2011
Materias:
Brief Definitive Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182059/
https://ncbi.nlm.nih.gov/pubmed/21875957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111083
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