Activation of GCN2/ATF4 signals in amygdalar PKC-δ neurons promotes WAT browning under leucine deprivation

The browning of white adipose tissue (WAT) has got much attention for its potential beneficial effects on metabolic disorders, however, the nutritional factors and neuronal signals involved remain largely unknown. We sought to investigate whether WAT browning is stimulated by leucine deprivation, an...

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Vydáno v:Nat Commun
Hlavní autoři: Yuan, Feixiang, Jiang, Haizhou, Yin, Hanrui, Jiang, Xiaoxue, Jiao, Fuxin, Chen, Shanghai, Ying, Hao, Chen, Yan, Zhai, Qiwei, Guo, Feifan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275074/
https://ncbi.nlm.nih.gov/pubmed/32504036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16662-2
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