Overexpression of Smad7 in hypothalamic POMC neurons disrupts glucose balance by attenuating central insulin signaling

OBJECTIVE: Although the hypothalamus is crucial for peripheral metabolism control, the signals in specific neurons involved remain poorly understood. The aim of our current study was to explore the role of the hypothalamic gene mothers against decapentaplegic homolog 7 (Smad7) in peripheral glucose...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Yuan, Feixiang, Yin, Hanrui, Deng, Yalan, Jiao, Fuxin, Jiang, Haizhou, Niu, Yuguo, Chen, Shanghai, Ying, Hao, Zhai, Qiwei, Chen, Yan, Guo, Feifan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551358/
https://ncbi.nlm.nih.gov/pubmed/32971298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101084
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