Overexpression of Smad7 in hypothalamic POMC neurons disrupts glucose balance by attenuating central insulin signaling

OBJECTIVE: Although the hypothalamus is crucial for peripheral metabolism control, the signals in specific neurons involved remain poorly understood. The aim of our current study was to explore the role of the hypothalamic gene mothers against decapentaplegic homolog 7 (Smad7) in peripheral glucose...

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Vydáno v:Mol Metab
Hlavní autoři: Yuan, Feixiang, Yin, Hanrui, Deng, Yalan, Jiao, Fuxin, Jiang, Haizhou, Niu, Yuguo, Chen, Shanghai, Ying, Hao, Zhai, Qiwei, Chen, Yan, Guo, Feifan
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551358/
https://ncbi.nlm.nih.gov/pubmed/32971298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101084
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