Cdc42 mediates cancer cell chemotaxis in perineural invasion

Perineural invasion (PNI) is an ominous form of cancer progression along nerves associated with poor clinical outcome. Glial derived neurotrophic factor (GDNF) interacts with cancer cell RET receptors to enable PNI, but downstream events remain undefined. We demonstrate that GDNF leads to early acti...

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Bibliografski detalji
Izdano u:Mol Cancer Res
Glavni autori: Chernichenko, Natalya, Omelchenko, Tatiana, Deborde, Sylvie, Bakst, Richard, He, Shizhi, Chen, Chun-Hao, Gusain, Laxmi, Vakiani, Efsevia, Katabi, Nora, Hall, Alan, Wong, Richard J
Format: Artigo
Jezik:Inglês
Izdano: 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272295/
https://ncbi.nlm.nih.gov/pubmed/32086369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0726
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