Histone Lysine Methylation Dynamics Control EGFR DNA Copy Number Amplification

Acquired chromosomal DNA copy gains are a feature of many tumors; however, the mechanisms that underpin oncogene amplification are poorly understood. Recent studies have begun to uncover the importance of epigenetic states and histone lysine methyltransferases (KMTs) and demethylases (KDMs) in regul...

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發表在:Cancer Discov
Main Authors: Clarke, Thomas L., Tang, Ran, Chakraborty, Damayanti, Rechem, Capucine Van, Ji, Fei, Mishra, Sweta, Ma, Anqi, Kaniskan, H. Ümit, Jin, Jian, Lawrence, Michael S., Sadreyev, Ruslan I., Whetstine, Johnathan R.
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271978/
https://ncbi.nlm.nih.gov/pubmed/31776131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-19-0463
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