Histone Lysine Methylation Dynamics Control EGFR DNA Copy Number Amplification

Acquired chromosomal DNA copy gains are a feature of many tumors; however, the mechanisms that underpin oncogene amplification are poorly understood. Recent studies have begun to uncover the importance of epigenetic states and histone lysine methyltransferases (KMTs) and demethylases (KDMs) in regul...

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Bibliografske podrobnosti
izdano v:Cancer Discov
Main Authors: Clarke, Thomas L., Tang, Ran, Chakraborty, Damayanti, Rechem, Capucine Van, Ji, Fei, Mishra, Sweta, Ma, Anqi, Kaniskan, H. Ümit, Jin, Jian, Lawrence, Michael S., Sadreyev, Ruslan I., Whetstine, Johnathan R.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271978/
https://ncbi.nlm.nih.gov/pubmed/31776131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-19-0463
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