Histone Lysine Methylation Dynamics Control EGFR DNA Copy Number Amplification

Acquired chromosomal DNA copy gains are a feature of many tumors; however, the mechanisms that underpin oncogene amplification are poorly understood. Recent studies have begun to uncover the importance of epigenetic states and histone lysine methyltransferases (KMTs) and demethylases (KDMs) in regul...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Discov
Prif Awduron: Clarke, Thomas L., Tang, Ran, Chakraborty, Damayanti, Rechem, Capucine Van, Ji, Fei, Mishra, Sweta, Ma, Anqi, Kaniskan, H. Ümit, Jin, Jian, Lawrence, Michael S., Sadreyev, Ruslan I., Whetstine, Johnathan R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271978/
https://ncbi.nlm.nih.gov/pubmed/31776131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-19-0463
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