Cross-talk Between Lysine Modifying Enzymes Controls Site-specific DNA Amplifications

Acquired chromosomal DNA amplifications are features of many tumors. Mechanisms directly controlling site-specific DNA copy gains are not well defined although overexpression and stabilization of the histone H3 lysine 9/36 (H3K9/36) tri-demethylase KDM4A generates transient site-specific copy number...

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Publicado en:Cell
Autores principales: Mishra, Sweta, Van Rechem, Capucine, Pal, Sangita, Clarke, Thomas L., Chakraborty, Damayanti, Mahan, Sarah, Black, Joshua C., Lawrence, Michael S., Daniels, Danette L., Whetstine, Johnathan R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212369/
https://ncbi.nlm.nih.gov/pubmed/30057114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.06.018
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