Prostate cancer cell‐intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone

The latency associated with bone metastasis emergence in castrate‐resistant prostate cancer is attributed to dormancy, a state in which cancer cells persist prior to overt lesion formation. Using single‐cell transcriptomics and ex vivo profiling, we have uncovered the critical role of tumor‐intrinsi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Owen, Katie L, Gearing, Linden J, Zanker, Damien J, Brockwell, Natasha K, Khoo, Weng Hua, Roden, Daniel L, Cmero, Marek, Mangiola, Stefano, Hong, Matthew K, Spurling, Alex J, McDonald, Michelle, Chan, Chia‐Ling, Pasam, Anupama, Lyons, Ruth J, Duivenvoorden, Hendrika M, Ryan, Andrew, Butler, Lisa M, Mariadason, John M, Giang Phan, Tri, Hayes, Vanessa M, Sandhu, Shahneen, Swarbrick, Alexander, Corcoran, Niall M, Hertzog, Paul J, Croucher, Peter I, Hovens, Chris, Parker, Belinda S
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271653/
https://ncbi.nlm.nih.gov/pubmed/32314873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050162
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados