Prostate cancer cell‐intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone

The latency associated with bone metastasis emergence in castrate‐resistant prostate cancer is attributed to dormancy, a state in which cancer cells persist prior to overt lesion formation. Using single‐cell transcriptomics and ex vivo profiling, we have uncovered the critical role of tumor‐intrinsi...

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Detaylı Bibliyografya
Yayımlandı:EMBO Rep
Asıl Yazarlar: Owen, Katie L, Gearing, Linden J, Zanker, Damien J, Brockwell, Natasha K, Khoo, Weng Hua, Roden, Daniel L, Cmero, Marek, Mangiola, Stefano, Hong, Matthew K, Spurling, Alex J, McDonald, Michelle, Chan, Chia‐Ling, Pasam, Anupama, Lyons, Ruth J, Duivenvoorden, Hendrika M, Ryan, Andrew, Butler, Lisa M, Mariadason, John M, Giang Phan, Tri, Hayes, Vanessa M, Sandhu, Shahneen, Swarbrick, Alexander, Corcoran, Niall M, Hertzog, Paul J, Croucher, Peter I, Hovens, Chris, Parker, Belinda S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271653/
https://ncbi.nlm.nih.gov/pubmed/32314873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050162
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