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Prostate cancer cell‐intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone

The latency associated with bone metastasis emergence in castrate‐resistant prostate cancer is attributed to dormancy, a state in which cancer cells persist prior to overt lesion formation. Using single‐cell transcriptomics and ex vivo profiling, we have uncovered the critical role of tumor‐intrinsi...

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書誌詳細
出版年:EMBO Rep
主要な著者: Owen, Katie L, Gearing, Linden J, Zanker, Damien J, Brockwell, Natasha K, Khoo, Weng Hua, Roden, Daniel L, Cmero, Marek, Mangiola, Stefano, Hong, Matthew K, Spurling, Alex J, McDonald, Michelle, Chan, Chia‐Ling, Pasam, Anupama, Lyons, Ruth J, Duivenvoorden, Hendrika M, Ryan, Andrew, Butler, Lisa M, Mariadason, John M, Giang Phan, Tri, Hayes, Vanessa M, Sandhu, Shahneen, Swarbrick, Alexander, Corcoran, Niall M, Hertzog, Paul J, Croucher, Peter I, Hovens, Chris, Parker, Belinda S
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271653/
https://ncbi.nlm.nih.gov/pubmed/32314873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050162
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