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Enzymatic studies of isoflavonoids as selective and potent inhibitors of human leukocyte 5-lipoxygenase
Continuing our search to find more potent and selective 5-LOX inhibitors, we present now the enzymatic evaluation of seventeen isoflavones (IR) and nine isoflavans (HIR), and their in vitro and in cellulo potency against human leukocyte 5-LOX. Of the 26 compounds tested, 10 isoflavones and 9 isoflav...
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| Publicado no: | Chem Biol Drug Des |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7270146/ https://ncbi.nlm.nih.gov/pubmed/25359714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12469 |
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