4-hydroxy-2(3H)-benzoxazolone alleviates acetaminophen-induced hepatic injury by inhibiting NF-κB and activating Nrf2/HO-1 signaling pathways

The purpose of this study is to evaluate the protective effect of 4-hydroxy-2(3H)-benzoxazolone from Acanthus ilicifolius (HBAI) on acute liver injury induced by acetaminophen in mice and its mechanism. Mice were continuously treated with HBAI (200, 100, 50 mg/kg) once a day for 10 days. After that,...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Am J Transl Res
Главные авторы: Wei, Xiugui, Wang, Hongyuan, Sun, Xuemei, Huang, Xiukun, Xu, Wanpeng, Liang, Yingqin, Liu, Lin, Mo, Siyan, Lin, Xing, Lin, Jun
Формат: Artigo
Язык:Inglês
Опубликовано: e-Century Publishing Corporation 2020
Предметы:
Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269977/
https://ncbi.nlm.nih.gov/pubmed/32509209
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы