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Ulinastatin protects against acetaminophen-induced liver injury by alleviating ferroptosis via the SIRT1/NRF2/HO-1 pathway

Acetaminophen (APAP) overdose has been considered responsible for the drug-induced liver injury for many years. Ferroptosis is defined as an iron-dependent form of cell death associated with lipid peroxide accumulation. Ferroptosis is involved in APAP-induced acute liver failure, and UTI is an effec...

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Bibliografische gegevens
Gepubliceerd in:Am J Transl Res
Hoofdauteurs: Wang, Cong, Liu, Tong, Tong, Yingmu, Cui, Ruixia, Qu, Kai, Liu, Chang, Zhang, Jingyao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8290678/
https://ncbi.nlm.nih.gov/pubmed/34306342
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