4-hydroxy-2(3H)-benzoxazolone alleviates acetaminophen-induced hepatic injury by inhibiting NF-κB and activating Nrf2/HO-1 signaling pathways

The purpose of this study is to evaluate the protective effect of 4-hydroxy-2(3H)-benzoxazolone from Acanthus ilicifolius (HBAI) on acute liver injury induced by acetaminophen in mice and its mechanism. Mice were continuously treated with HBAI (200, 100, 50 mg/kg) once a day for 10 days. After that,...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Am J Transl Res
Hlavní autoři: Wei, Xiugui, Wang, Hongyuan, Sun, Xuemei, Huang, Xiukun, Xu, Wanpeng, Liang, Yingqin, Liu, Lin, Mo, Siyan, Lin, Xing, Lin, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2020
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269977/
https://ncbi.nlm.nih.gov/pubmed/32509209
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky