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Presynaptic APP levels and synaptic homeostasis are regulated by Akt phosphorylation of huntingtin

Studies have suggested that amyloid precursor protein (APP) regulates synaptic homeostasis, but the evidence has not been consistent. In particular, signaling pathways controlling APP transport to the synapse in axons and dendrites remain to be identified. Having previously shown that Huntingtin (HT...

詳細記述

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書誌詳細
出版年:eLife
主要な著者: Bruyère, Julie, Abada, Yah-Se, Vitet, Hélène, Fontaine, Gaëlle, Deloulme, Jean-Christophe, Cès, Aurélia, Denarier, Eric, Pernet-Gallay, Karin, Andrieux, Annie, Humbert, Sandrine, Potier, Marie-Claude, Delatour, Benoît, Saudou, Frédéric
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269668/
https://ncbi.nlm.nih.gov/pubmed/32452382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56371
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