Telacebec for Ultrashort Treatment of Buruli Ulcer in a Mouse Model

Telacebec (Q203) is a new antitubercular drug with extremely potent activity against Mycobacterium ulcerans. Here, we explored the treatment-shortening potential of Q203 alone or in combination with rifampin (RIF) in a mouse footpad infection model. The first study compared Q203 at 5 and 10 mg/kg do...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Almeida, Deepak V., Converse, Paul J., Omansen, Till F., Tyagi, Sandeep, Tasneen, Rokeya, Kim, Jeongjun, Nuermberger, Eric L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Clinical Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269501/
https://ncbi.nlm.nih.gov/pubmed/32205344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00259-20
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