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Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer

Starting in 2004, the standard regimen for treatment of Buruli ulcer (BU) recommended by the World Health Organization has been daily treatment for eight weeks with rifampin (RIF) and streptomycin. Based on recent clinical trials, treatment with an all-oral regimen of RIF and clarithromycin (CLR) ma...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Converse, Paul J., Almeida, Deepak V., Tasneen, Rokeya, Saini, Vikram, Tyagi, Sandeep, Ammerman, Nicole C., Li, Si-Yang, Anders, Nicole M., Rudek, Michelle A., Grosset, Jacques H., Nuermberger, Eric L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107292/
https://ncbi.nlm.nih.gov/pubmed/30102705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006728
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