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Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer

Starting in 2004, the standard regimen for treatment of Buruli ulcer (BU) recommended by the World Health Organization has been daily treatment for eight weeks with rifampin (RIF) and streptomycin. Based on recent clinical trials, treatment with an all-oral regimen of RIF and clarithromycin (CLR) ma...

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Détails bibliographiques
Publié dans:PLoS Negl Trop Dis
Auteurs principaux: Converse, Paul J., Almeida, Deepak V., Tasneen, Rokeya, Saini, Vikram, Tyagi, Sandeep, Ammerman, Nicole C., Li, Si-Yang, Anders, Nicole M., Rudek, Michelle A., Grosset, Jacques H., Nuermberger, Eric L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107292/
https://ncbi.nlm.nih.gov/pubmed/30102705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006728
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