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Synthesis of 3-O-Sulfated Disaccharide and Tetrasaccharide Standards for Compositional Analysis of Heparan Sulfate

3-O-Sulfation on the glucosamine sugar unit in heparan sulfate (HS) is linked to various biological functions, including the anticoagulant activity to treat thrombotic disorders in hospitals. The 3-O-sulfated glucosamine is biosynthesized by heparan sulfate glucosamine 3-sulfotransferases. Because o...

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Détails bibliographiques
Publié dans:Biochemistry
Auteurs principaux: Dhurandhare, Vijay Manohar, Pagadala, Vijayakanth, Ferreira, Andreia, De Muynck, Louis, Liu, Jian
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269455/
https://ncbi.nlm.nih.gov/pubmed/31608625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00838
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