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Severe familial hypercholesterolemia impairs the regulation of coronary blood flow and oxygen supply during exercise

Accelerated development of coronary atherosclerosis is a defining characteristic of familial hypercholesterolemia (FH). However, recent data highlight significant cardiovascular risk prior to the development of critical coronary stenosis. We, therefore, examined the hypothesis that FH produces coron...

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Détails bibliographiques
Publié dans:Basic Res Cardiol
Auteurs principaux: Bender, Shawn B., de Beer, Vincent J., Tharp, Darla L., Bowles, Douglas K., Laughlin, M. Harold, Merkus, Daphne, Duncker, Dirk J.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269332/
https://ncbi.nlm.nih.gov/pubmed/27624732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-016-0579-9
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