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Familial hypercholesterolemia impairs exercise-induced systemic vasodilation due to reduced NO bioavailability
Hypercholesterolemia impairs endothelial function [e.g., the nitric oxide (NO)-cyclic GMP-phosphodiesterase 5 (PDE5) pathway], limits shear stress-induced vasodilation, and is therefore expected to reduce exercise-induced vasodilation. To assess the actual effects of hypercholesterolemia on endothel...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3882941/ https://ncbi.nlm.nih.gov/pubmed/24157527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00619.2013 |
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