Effects of Recombinant human leptin (Metreleptin) on nocturnal LH secretion in lipodystrophy patients

BACKGROUND: Leptin replacement in patients with leptin gene mutations improves hypogonadotropic hypogonadism. The effects of leptin replacement on LH secretion in patients with lipodystrophy are unknown. AIM: We examined nocturnal LH secretory dynamics on and off exogenous leptin therapy using a 2 p...

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Bibliographic Details
Published in:Neuroendocrinology
Main Authors: Abel, Brent S., Muniyappa, Ranganath, Stratton, Pamela, Skarulis, Monica C., Gorden, Phillip, Brown, Rebecca J.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269156/
https://ncbi.nlm.nih.gov/pubmed/26336809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000439432
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