Effects of Leptin Replacement Therapy on Pancreatic β-Cell Function in Patients With Lipodystrophy

OBJECTIVE: Leptin administration is known to directly modulate pancreatic β-cell function in leptin-deficient rodent models. However, human studies examining the effects of leptin administration on β-cell function are lacking. In this study, we examined the effects (16–20 weeks) of leptin replacemen...

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Autores principales: Muniyappa, Ranganath, Brown, Rebecca J., Mari, Andrea, Joseph, Jalaja, Warren, Mary A., Cochran, Elaine K., Skarulis, Monica C., Gorden, Phillip
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2014
Materias:
Pathophysiology/Complications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964492/
https://ncbi.nlm.nih.gov/pubmed/24496806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc13-2040
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