Metreleptin Therapy Lowers Plasma Angiopoietin-like protein 3 (ANGPTL3) in Patients with Generalized Lipodystrophy

BACKGROUND: Reduced triglyceride clearance due to impaired lipoprotein lipase (LPL)-mediated lipolysis contributes to severe hypertriglyceridemia in lipodystrophy. Angiopoietin-like protein 3 (ANGPTL3) and 4 (ANGPTL4) impair clearance of triglycerides by inhibiting LPL. Whether circulating ANGPTL3/4...

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Xehetasun bibliografikoak
Argitaratua izan da:J Clin Lipidol
Egile Nagusiak: Muniyappa, Ranganath, Abel, Brent S., Asthana, Asha, Walter, Mary F., Cochran, Elaine K., Remaley, Alan T., Skarulis, Monica C., Gorden, Phillip, Brown, Rebecca J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433252/
https://ncbi.nlm.nih.gov/pubmed/28502512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacl.2017.02.002
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