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Metreleptin Therapy Lowers Plasma Angiopoietin-like protein 3 (ANGPTL3) in Patients with Generalized Lipodystrophy
BACKGROUND: Reduced triglyceride clearance due to impaired lipoprotein lipase (LPL)-mediated lipolysis contributes to severe hypertriglyceridemia in lipodystrophy. Angiopoietin-like protein 3 (ANGPTL3) and 4 (ANGPTL4) impair clearance of triglycerides by inhibiting LPL. Whether circulating ANGPTL3/4...
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| Publicado no: | J Clin Lipidol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5433252/ https://ncbi.nlm.nih.gov/pubmed/28502512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacl.2017.02.002 |
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