Effects of Metreleptin in Pediatric Patients With Lipodystrophy

CONTEXT: Lipodystrophy syndromes are rare disorders of deficient adipose tissue. Metreleptin, a human analog of leptin, improved metabolic abnormalities in mixed cohorts of children and adults with lipodystrophy and low leptin. OBJECTIVE: Determine effects of metreleptin on diabetes, hyperlipidemia,...

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Publicado en:J Clin Endocrinol Metab
Autores principales: Brown, Rebecca J., Meehan, Cristina Adelia, Cochran, Elaine, Rother, Kristina I., Kleiner, David E., Walter, Mary, Gorden, Phillip
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2017
Materias:
Clinical Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443330/
https://ncbi.nlm.nih.gov/pubmed/28324110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-3628
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