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Long-term effectiveness and safety of metreleptin in the treatment of patients with generalized lipodystrophy

PURPOSE: The purpose of this study is to summarize the effectiveness and safety of metreleptin in patients with congenital or acquired generalized lipodystrophy. METHODS: Patients (N=66) aged ≥6 months had lipodystrophy, low circulating leptin, and ≥1 metabolic abnormality (diabetes mellitus, insuli...

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Detalhes bibliográficos
Publicado no:Endocrine
Main Authors: Brown, Rebecca J., Oral·, Elif A., Cochran, Elaine, Araújo-Vilar, David, Savage, David B., Long, Alison, Fine, Gregory, Salinardi, Taylor, Gorden, Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936645/
https://ncbi.nlm.nih.gov/pubmed/29644599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12020-018-1589-1
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