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Long-term effectiveness and safety of metreleptin in the treatment of patients with partial lipodystrophy

PURPOSE: To evaluate the effects of metreleptin in patients with partial lipodystrophy (PL). METHODS: Patients aged ≥6 months with PL, circulating leptin <12.0 ng/mL, and diabetes mellitus, insulin resistance, or hypertriglyceridemia received metreleptin doses (once or twice daily) titrated to a...

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Publicado en:Endocrine
Main Authors: Oral, Elif A., Gorden, Phillip, Cochran, Elaine, Araújo-Vilar, David, Savage, David B., Long, Alison, Fine, Gregory, Salinardi, Taylor, Brown, Rebecca
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340120/
https://ncbi.nlm.nih.gov/pubmed/30805888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12020-019-01862-8
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