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Copper-mediated Fluorination of Aryl Trisiloxanes with Nucleophilic Fluoride

A method for the nucleophilic fluorination of heptamethyl aryl trisiloxanes to form fluoroarenes is reported. The reaction proceeds in the presence of Cu(OTf)(2) and KHF(2) as the fluoride source under mild conditions for a broad range of heptamethyltrisiloxyarenes with high functional group toleran...

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Bibliografiske detaljer
Udgivet i:Chemistry
Main Authors: Dorel, Ruth, Boehm, Philip, Schwinger, Daniel P., Hartwig, John F.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266656/
https://ncbi.nlm.nih.gov/pubmed/31872488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201905040
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