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Copper-mediated Fluorination of Aryl Trisiloxanes with Nucleophilic Fluoride

A method for the nucleophilic fluorination of heptamethyl aryl trisiloxanes to form fluoroarenes is reported. The reaction proceeds in the presence of Cu(OTf)(2) and KHF(2) as the fluoride source under mild conditions for a broad range of heptamethyltrisiloxyarenes with high functional group toleran...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Dorel, Ruth, Boehm, Philip, Schwinger, Daniel P., Hartwig, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266656/
https://ncbi.nlm.nih.gov/pubmed/31872488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201905040
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