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CRISPR‐TAPE: protein‐centric CRISPR guide design for targeted proteome engineering
Rational molecular engineering of proteins with CRISPR‐based approaches is challenged by the gene‐centric nature of gRNA design tools. To address this, we have developed CRISPR‐TAPE, a protein‐centric gRNA design algorithm that allows users to target specific residues, or amino acid types within pro...
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| Publicado no: | Mol Syst Biol |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7266498/ https://ncbi.nlm.nih.gov/pubmed/32485092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20209475 |
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