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Accounting for long-range correlations in genome-wide simulations of large cohorts

Coalescent simulations are widely used to examine the effects of evolution and demographic history on the genetic makeup of populations. Thanks to recent progress in algorithms and data structures, simulators such as the widely-used msprime now provide genome-wide simulations for millions of individ...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Genet
Prif Awduron: Nelson, Dominic, Kelleher, Jerome, Ragsdale, Aaron P., Moreau, Claudia, McVean, Gil, Gravel, Simon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266353/
https://ncbi.nlm.nih.gov/pubmed/32369493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008619
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