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Accounting for long-range correlations in genome-wide simulations of large cohorts

Coalescent simulations are widely used to examine the effects of evolution and demographic history on the genetic makeup of populations. Thanks to recent progress in algorithms and data structures, simulators such as the widely-used msprime now provide genome-wide simulations for millions of individ...

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Detalles Bibliográficos
Publicado en:PLoS Genet
Autores principales: Nelson, Dominic, Kelleher, Jerome, Ragsdale, Aaron P., Moreau, Claudia, McVean, Gil, Gravel, Simon
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266353/
https://ncbi.nlm.nih.gov/pubmed/32369493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008619
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