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Accounting for long-range correlations in genome-wide simulations of large cohorts

Coalescent simulations are widely used to examine the effects of evolution and demographic history on the genetic makeup of populations. Thanks to recent progress in algorithms and data structures, simulators such as the widely-used msprime now provide genome-wide simulations for millions of individ...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Nelson, Dominic, Kelleher, Jerome, Ragsdale, Aaron P., Moreau, Claudia, McVean, Gil, Gravel, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266353/
https://ncbi.nlm.nih.gov/pubmed/32369493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008619
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