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Stratification and prediction of drug synergy based on target functional similarity

Drug combinations can expand therapeutic options and address cancer’s resistance. However, the combinatorial space is enormous precluding its systematic exploration. Therefore, synergy prediction strategies are essential. We here present an approach to prioritise drug combinations in high-throughput...

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Bibliografische gegevens
Gepubliceerd in:NPJ Syst Biol Appl
Hoofdauteurs: Yang, Mi, Jaaks, Patricia, Dry, Jonathan, Garnett, Mathew, Menden, Michael P., Saez-Rodriguez, Julio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265486/
https://ncbi.nlm.nih.gov/pubmed/32487991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-020-0136-x
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