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Colistin for the treatment of urinary tract infections caused by extremely drug-resistant Pseudomonas aeruginosa: a call for a dose update
OBJECTIVES: Optimal dosage regimens of colistin for the treatment of urinary tract infections (UTI) are unknown. Colistimethate sodium (CMS), the inactive prodrug of colistin, is mainly excreted in urine and converts to colistin after filtration by glomeruli, suggesting that concentrations of colist...
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| Опубликовано в: : | J Infect |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7265153/ https://ncbi.nlm.nih.gov/pubmed/31265867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinf.2019.06.011 |
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