Colistin for the treatment of urinary tract infections caused by extremely drug-resistant Pseudomonas aeruginosa: a call for a dose update

OBJECTIVES: Optimal dosage regimens of colistin for the treatment of urinary tract infections (UTI) are unknown. Colistimethate sodium (CMS), the inactive prodrug of colistin, is mainly excreted in urine and converts to colistin after filtration by glomeruli, suggesting that concentrations of colist...

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Detalhes bibliográficos
Publicado no:J Infect
Main Authors: Sorlí, Luisa, Luque, Sonia, Li, Jian, Campillo, Núria, Danés, Marc, Montero, Milagro, Segura, Concha, Grau, Santiago, Horcajada, Juan Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265153/
https://ncbi.nlm.nih.gov/pubmed/31265867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinf.2019.06.011
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