Impact of colistin plasma levels on the clinical outcome of patients with infections caused by extremely drug-resistant Pseudomonas aeruginosa

BACKGROUND: Colistin has a narrow therapeutic window with nephrotoxicity being the major dose-limiting adverse effect. Currently, the optimal doses and therapeutic plasma levels are unknown. METHODS: Prospective observational cohort study, including patients infected by colistin-susceptible P. aerug...

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Detalhes bibliográficos
Publicado no:BMC Infect Dis
Main Authors: Sorlí, Luisa, Luque, Sonia, Segura, Concepción, Campillo, Nuria, Montero, Milagro, Esteve, Erika, Herrera, Sabina, Benito, Natividad, Alvarez-Lerma, Francisco, Grau, Santiago, Horcajada, Juan Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217330/
https://ncbi.nlm.nih.gov/pubmed/28056821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-016-2117-7
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