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Electroosmosis Dominates Electrophoresis of Antibiotic Transport Across the Outer Membrane Porin F

We report that the dynamics of antibiotic capture and transport across a voltage-biased OmpF nanopore is dominated by the electroosmotic flow rather than the electrophoretic force. By reconstituting an OmpF porin in an artificial lipid bilayer and applying an electric field across it, we are able to...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Bafna, Jayesh A., Pangeni, Sushil, Winterhalter, Mathias, Aksoyoglu, M. Alphan
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264812/
https://ncbi.nlm.nih.gov/pubmed/32348725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.04.011
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