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Fosfomycin Permeation through the Outer Membrane Porin OmpF

Fosfomycin is a frequently prescribed drug in the treatment of acute urinary tract infections. It enters the bacterial cytoplasm and inhibits the biosynthesis of peptidoglycans by targeting the MurA enzyme. Despite extensive pharmacological studies and clinical use, the permeability of fosfomycin ac...

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Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Golla, Vinaya Kumar, Sans-Serramitjana, Eulàlia, Pothula, Karunakar Reddy, Benier, Lorraine, Bafna, Jayesh Arun, Winterhalter, Mathias, Kleinekathöfer, Ulrich
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350074/
https://ncbi.nlm.nih.gov/pubmed/30616836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.12.002
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