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Fosfomycin Permeation through the Outer Membrane Porin OmpF

Fosfomycin is a frequently prescribed drug in the treatment of acute urinary tract infections. It enters the bacterial cytoplasm and inhibits the biosynthesis of peptidoglycans by targeting the MurA enzyme. Despite extensive pharmacological studies and clinical use, the permeability of fosfomycin ac...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Golla, Vinaya Kumar, Sans-Serramitjana, Eulàlia, Pothula, Karunakar Reddy, Benier, Lorraine, Bafna, Jayesh Arun, Winterhalter, Mathias, Kleinekathöfer, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350074/
https://ncbi.nlm.nih.gov/pubmed/30616836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.12.002
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