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Understanding Ion Conductance on a Molecular Level: An All-Atom Modeling of the Bacterial Porin OmpF

All-atom molecular dynamics simulations of the ion current through OmpF, the major porin in the outer membrane of Escherichia coli, were performed. Starting from the crystal structure, the all-atom modeling allows us to calculate a parameter-free ion conductance in semiquantitative agreement with ex...

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Detalhes bibliográficos
Main Authors: Pezeshki, Soroosh, Chimerel, Catalin, Bessonov, Andrey N., Winterhalter, Mathias, Kleinekathöfer, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756365/
https://ncbi.nlm.nih.gov/pubmed/19804720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.07.018
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