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Postnatal loss of the insulin receptor in osteoprogenitor cells does not impart a metabolic phenotype

The relationship between osteoblast-specific insulin signaling, osteocalcin activation and gluco-metabolic homeostasis has proven to be complex and potentially inconsistent across animal-model systems and in humans. Moreover, the impact of postnatally acquired, osteoblast-specific insulin deficiency...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fowlkes, John L., Clay Bunn, R., Kalaitzoglou, Evangelia, Ray, Phil, Popescu, Iuliana, Thrailkill, Kathryn M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264347/
https://ncbi.nlm.nih.gov/pubmed/32483283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65717-3
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